English Intern
    Institut für Virologie und Immunbiologie

    Selected Publications:

     

    Prottengeier, J., Koutsilieri, E., and Scheller, C. 2014. The effects of opioids on HIV reactivation in latently-infected T-lymphoblasts. AIDS Res Ther 11:17.

    Koutsilieri, E., Riederer, P., du Plessis, S., and Scheller, C. 2014. A short review on the relation between the dopamine transporter 10/10-repeat allele and ADHD: implications for HIV infection. Atten Defic Hyperact Disord 6:203-209.

    Armbruster, N., Weber, C., Wictorowicz, T., Rethwilm, A., Scheller, C., and Steinert, A.F. 2014. Ex vivo gene delivery to synovium using foamy viral vectors. J Gene Med 16:166-178.

    Weber, C., Armbruster, N., Scheller, C., Kreppel, F., Kochanek, S., Rethwilm, A., and Steinert, A.F. 2013. Foamy virus-adenovirus hybrid vectors for gene therapy of the arthritides. J Gene Med 15:155-167.

    Koutsilieri, E., Lutz, M.B., and Scheller, C. 2013. Autoimmunity, dendritic cells and relevance for Parkinson's disease. J Neural Transm 120:75-81.

    Horn, A., Scheller, C., du Plessis, S., Arendt, G., Nolting, T., Joska, J., Sopper, S., Maschke, M., Obermann, M., Husstedt, I.W., et al. 2013. Increases in CSF dopamine in HIV patients are due to the dopamine transporter 10/10-repeat allele which is more frequent in HIV-infected individuals. J Neural Transm 120:1411-1419.

    Plochmann, K., Horn, A., Gschmack, E., Armbruster, N., Krieg, J., Wiktorowicz, T., Weber, C., Stirnnagel, K., Lindemann, D., Rethwilm, A., et al. 2012. Heparan sulfate is an attachment factor for foamy virus entry. J Virol 86:10028-10035.

    Oberlander, U., Pletinckx, K., Dohler, A., Muller, N., Lutz, M.B., Arzberger, T., Riederer, P., Gerlach, M., Koutsilieri, E., and Scheller, C. 2011. Neuromelanin is an immune stimulator for dendritic cells in vitro. BMC Neurosci 12:116.

    Kasang, C., Kalluvya, S., Majinge, C., Stich, A., Bodem, J., Kongola, G., Jacobs, G.B., Mlewa, M., Mildner, M., Hensel, I., et al. 2011. HIV drug resistance (HIVDR) in antiretroviral therapy-naive patients in Tanzania not eligible for WHO threshold HIVDR survey is dramatically high. PLoS One 6:e23091.

    Scheller, C., Arendt, G., Nolting, T., Antke, C., Sopper, S., Maschke, M., Obermann, M., Angerer, A., Husstedt, I.W., Meisner, F., et al. 2010. Increased dopaminergic neurotransmission in therapy-naive asymptomatic HIV patients is not associated with adaptive changes at the dopaminergic synapses. J Neural Transm 117:699-705.

    Gartner, K., Wiktorowicz, T., Park, J., Mergia, A., Rethwilm, A., and Scheller, C. 2009. Accuracy estimation of foamy virus genome copying. Retrovirology 6:32.

    Spiliotis, M., Lechner, S., Tappe, D., Scheller, C., Krohne, G., and Brehm, K. 2008. Transient transfection of Echinococcus multilocularis primary cells and complete in vitro regeneration of metacestode vesicles. Int J Parasitol 38:1025-1039.

    Meisner, F., Scheller, C., Kneitz, S., Sopper, S., Neuen-Jacob, E., Riederer, P., ter Meulen, V., Koutsilieri, E., and German Competence Network, H.A. 2008. Memantine upregulates BDNF and prevents dopamine deficits in SIV-infected macaques: a novel pharmacological action of memantine. Neuropsychopharmacology 33:2228-2236.

    Meisner, F., Neuen-Jacob, E., Sopper, S., Schmidt, M., Schlammes, S., Scheller, C., Vosswinkel, D., Ter Meulen, V., Riederer, P., and Koutsilieri, E. 2008. Disruption of excitatory amino acid transporters in brains of SIV-infected rhesus macaques is associated with microglia activation. J Neurochem 104:202-209.

    Plochmann, K., Korte, G., Koutsilieri, E., Richling, E., Riederer, P., Rethwilm, A., Schreier, P., and Scheller, C. 2007. Structure-activity relationships of flavonoid-induced cytotoxicity on human leukemia cells. Arch Biochem Biophys 460:1-9.

    Koutsilieri, E., Rethwilm, A., and Scheller, C. 2007. The therapeutic potential of siRNA in gene therapy of neurodegenerative disorders. J Neural Transm Suppl:43-49.

    Kneitz, S., Meisner, F., Sopper, S., Kaiser, F., Grunblatt, E., Scheller, C., Riederer, P., ter Meulen, V., and Koutsilieri, E. 2007. Biostatistical analysis of gene microarrays reveals diverse expression clusters between macaque subspecies in brain SIV infection. J Neural Transm Suppl:317-322.

    Scheller, C., Riederer, P., Gerlach, M., and Koutsilieri, E. 2006. Apoptosis inhibition in T cells triggers the expression of proinflammatory cytokines--implications for the CNS. J Neural Transm Suppl:45-51.

    Scheller, C., Knoferle, J., Ullrich, A., Prottengeier, J., Racek, T., Sopper, S., Jassoy, C., Rethwilm, A., and Koutsilieri, E. 2006. Caspase inhibition in apoptotic T cells triggers necrotic cell death depending on the cell type and the proapoptotic stimulus. J Cell Biochem 97:1350-1361.

    Scheller, C., Sopper, S., Jenuwein, M., Neuen-Jacob, E., Tatschner, T., Grunblatt, E., ter Meulen, V., Riederer, P., and Koutsilieri, E. 2005. Early impairment in dopaminergic neurotransmission in brains of SIV-infected rhesus monkeys due to microglia activation. J Neurochem 95:377-387.

    Li, J., Scheller, C., Koutsilieri, E., Griffiths, F., Beart, P.M., Mercer, L.D., Halliday, G., Kettle, E., Rowe, D., Riederer, P., et al. 2005. Differential effects of human neuromelanin and synthetic dopamine melanin on neuronal and glial cells. J Neurochem 95:599-608.

    Scheller, C., Ullrich, A., McPherson, K., Hefele, B., Knoferle, J., Lamla, S., Olbrich, A.R., Stocker, H., Arasteh, K., ter Meulen, V., et al. 2004. CpG oligodeoxynucleotides activate HIV replication in latently infected human T cells. J Biol Chem 279:21897-21902.

    Koutsilieri, E., Scheller, C., ter Meulen, V., and Riederer, P. 2004. Monoamine oxidase inhibition and CNS immunodeficiency infection. Neurotoxicology 25:267-270.

    Jenuwein, M., Scheller, C., Neuen-Jacob, E., Sopper, S., Tatschner, T., ter Meulen, V., Riederer, P., and Koutsilieri, E. 2004. Dopamine deficits and regulation of the cAMP second messenger system in brains of simian immunodeficiency virus-infected rhesus monkeys. J Neurovirol 10:163-170.

    Sopper, S., Nierwetberg, D., Halbach, A., Sauer, U., Scheller, C., Stahl-Hennig, C., Matz-Rensing, K., Schafer, F., Schneider, T., ter Meulen, V., et al. 2003. Impact of simian immunodeficiency virus (SIV) infection on lymphocyte numbers and T-cell turnover in different organs of rhesus monkeys. Blood 101:1213-1219.

    Scheller, C., Sopper, S., Koutsilieri, E., Ludwig, S., Ter Meulen, V., and Jassoy, C. 2003. Caspase inhibitors as a supplement in immune activation therapies to achieve eradication of HIV in its latent reservoirs. Ann N Y Acad Sci 1010:209-212.

    Sopper, S., Koutsilieri, E., Scheller, C., Czub, S., Riederer, P., and ter Meulen, V. 2002. Macaque animal model for HIV-induced neurological disease. J Neural Transm 109:747-766.

    Scheller, C., Sopper, S., Ehrhardt, C., Flory, E., Chen, P., Koutsilieri, E., Ludwig, S., ter Meulen, V., and Jassoy, C. 2002. Caspase inhibitors induce a switch from apoptotic to proinflammatory signaling in CD95-stimulated T lymphocytes. Eur J Immunol 32:2471-2480.

    Scheller, C., Sopper, S., Chen, P., Flory, E., Koutsilieri, E., Racek, T., Ludwig, S., ter Meulen, V., and Jassoy, C. 2002. Caspase inhibition activates HIV in latently infected cells. Role of tumor necrosis factor receptor 1 and CD95. J Biol Chem 277:15459-15464.

    Koutsilieri, E., Sopper, S., Scheller, C., ter Meulen, V., and Riederer, P. 2002. Involvement of dopamine in the progression of AIDS Dementia Complex. J Neural Transm 109:399-410.

    Koutsilieri, E., Sopper, S., Scheller, C., ter Meulen, V., and Riederer, P. 2002. Parkinsonism in HIV dementia. J Neural Transm 109:767-775.

    Koutsilieri, E., Scheller, C., Sopper, S., ter Meulen, V., and Riederer, P. 2002. The pathogenesis of HIV-induced dementia. Mech Ageing Dev 123:1047-1053.

    Scheller, C., and Jassoy, C. 2001. Syncytium formation amplifies apoptotic signals: a new view on apoptosis in HIV infection in vitro. Virology 282:48-55.

    Koutsilieri, E., Scheller, C., Sopper, S., Gotz, M.E., Gerlach, M., Meulen, V., and Riederer, P. 2001. Selegiline completely restores choline acetyltransferase activity deficits in simian immunodeficiency infection. Eur J Pharmacol 411:R1-R2.

    Strupp, W., Weidinger, G., Scheller, C., Ehret, R., Ohnimus, H., Girschick, H., Tas, P., Flory, E., Heinkelein, M., and Jassoy, C. 2000. Treatment of cells with detergent activates caspases and induces apoptotic cell death. J Membr Biol 175:181-189.

    Stocker, H., Scheller, C., and Jassoy, C. 2000. Destruction of primary CD4(+) T cells by cell-cell interaction in human immunodeficiency virus type 1 infection in vitro. J Gen Virol 81:1907-1911.

    Scheller, C., Sopper, S., Jassoy, C., ter Meulen, V., Riederer, P., and Koutsilieri, E. 2000. Dopamine activates HIV in chronically infected T lymphoblasts. J Neural Transm 107:1483-1489.

    Koutsilieri, E., Czub, S., Scheller, C., Sopper, S., Tatschner, T., Stahl-Hennig, C., ter Meulen, V., and Riederer, P. 2000. Brain choline acetyltransferase reduction in SIV infection. An index of early dementia? Neuroreport 11:2391-2393.

    Flory, E., Kunz, M., Scheller, C., Jassoy, C., Stauber, R., Rapp, U.R., and Ludwig, S. 2000. Influenza virus-induced NF-kappaB-dependent gene expression is mediated by overexpression of viral proteins and involves oxidative radicals and activation of IkappaB kinase. J Biol Chem 275:8307-8314.

    Koutsilieri, E., Sopper, S., Heinemann, T., Scheller, C., Lan, J., Stahl-Hennig, C., ter Meulen, V., Riederer, P., and Gerlach, M. 1999. Involvement of microglia in cerebrospinal fluid glutamate increase in SIV-infected rhesus monkeys (Macaca mulatta). AIDS Res Hum Retroviruses 15:471-477.

    Hofmann, F., Ohnimus, H., Scheller, C., Strupp, W., Zimmermann, U., and Jassoy, C. 1999. Electric field pulses can induce apoptosis. J Membr Biol 169:103-109.

     

    Kontakt

    Institut für Virologie und Immunbiologie
    Versbacher Straße 7
    97078 Würzburg

    E-Mail

    Suche Ansprechpartner

    Medizin, Geb. E5